Need some advice on my setup in Ableton

So I have a setup where the presets on Omnisphere are automated to change depending on which bar the marker is, however, I want to to have different settings on MG2 for each preset on Omnisphere, how would you approach this without taking a big load on my laptop?

Edit: the 4 and 5 tracks are just backing tracks, the chain is Audio interface>MG2 track>Midi Control with an instrument rack>Omnisphere with different presets.

you can switch presets in MG: you’ll have to send Program Changes to MG to make this work. The output of a midi track can be used as midi input on the MG audio track.