I am trying to activate my midiguitar 3 - it is stating that I do not have a default app to open it and I cannot open to activate
Im guessing you are trying to open the license file?
Please see FAQ:
For MG v3 you don’t need the license file at all. It will ask for your email and send you a code.
Also, note that it can take a little time to receive the email. I remember finding that part confusing, there was no message about a mail having been sent, as far as I recall.